ScreenFect GmbH公司由Pavel Levkin博士和Gary Davidson博士于2012年创立，是德国卡尔斯鲁厄理工学院 (KIT) 成功跨学科研究合作的成果，是创新化学领域与生物学和细胞筛选领域相结合，使技术从学术环境快速转移到商业企业。凭借新的专利技术，ScreenFect GmbH公司继续扩大其用于转染不同细胞的新型化学品和试剂的产品目录。在全球有着越来越多的合作伙伴，促进了ScreenFect^®产品的销售。

将质粒DNA或siRNA等核酸递送到细胞中是生物学研究的基础。由于其易用性和安全处理，对更高效的非病毒载体的需求很高。我们开发了一种基于点击化学的简单模块化方法，用于脂质样分子文库的平行合成。通过基于细胞的高通量筛选选择候选分子，然后进行广泛的优化以产生特定的转染试剂。ScreenFect GmbH已经合成了300多种化学物质，其中一些在不同细胞类型中显示出高效的转染，超过了几种流行的商业转染试剂的效率。我们开发了一系列多用途以及更专业的转染试剂，包括ScreenFect^® A、ScreenFect^® siRNA和ScreenFect^®mRNA和ScreenFect^®65。

Screen Fect^®转染试剂是使用组合化学方法开发的，并已获得专利，该方法可生成化学库。使用这些化学库，通过高通量细胞筛选方法鉴定候选试剂。最后，针对特定应用进一步优化最佳试剂。Screen Fect^®转染试剂可用于核酸分子（pDNA、siRNA、mRNA、miRNA）的转染以及它们的组合的共转染。Screen Fect^®试剂在许多标准细胞系以及难以转染的原代细胞和干细胞中具有出色的性能。

ScreenFect GmbH was founded in 2012 by Dr Pavel Levkin and Dr Gary Davidson as the result of a successful interdisciplinary research collaboration at the Karlsruhe Institute of Technology (KIT), Germany. Innovative chemistry in Dr Levkin's group combined with the biological and cell screening expertise in Dr Davidson's group allowed rapid transfer of technology from an academic setting to a commercial business.

Delivery of nucleic acids such as plasmid DNA or siRNA into cells is fundamental for biological research. There is a high demand for more efficient non-viral vectors due to their ease of use and safe handling. We have developed a facile modular method based on click chemistry for parallel synthesis of libraries of lipid-like molecules. Candidate molecules are selected by cell-based high throughput screenings and then undergo extensive optimization to generate specific transfection reagents. Over 300 chemicals have been synthesized and several of them showed highly efficient transfection in different cell types, surpassing the efficiency of several popular commercial transfection reagents. We have developed a range of multi purpose as well as more specialized transfection reagents, including ScreenFect^®A, ScreenFect^®siRNA and ScreenFect^®mRNA and ScreenFect^®65.

With new patented technologies ScreenFect GmbH continues to expanding their repertoire of novel chemicals and reagents for the transfection of diverse cells. Sales and distribution are promoted by a growing list of worldwide partners.

ScreenFect常卖产品：

靶点科技（北京）有限公司是ScreenFect在中国的官方授权代理商。被官方授权在中国负责品牌宣传推广，产品售前咨询和售后服务等一切商业活动和行为。靶点科技有专业技术团队，竭力为广大中国客户提供全方位的产品和服务赋能支持。

ScreenFect官网中文网站：www.ScreenFect.com.cn（筹备中……）

ScreenFect官网英文网站：www.ScreenFect.com