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Doccol 是一家从解决生物研究中的实际问题开始的生物技术公司。 2004 年,Doccol 确定了实验性中风研究中的一个关键问题是中风模型的质量不一致,因此通过提供标准化的封堵器,硅橡胶涂层单丝,用于大脑中动脉闭塞 (MCAO),为此提供了解决方案。这些MCAO封堵器深受卒中研究人员的喜爱,并被命名为“MCAO缝合线”。我们精致的硅橡胶涂层单丝是专门为诱导 MCAO 的管腔内丝模型而设计和制造的,该模型已广泛用于体内实验性中风研究。使用 Doccol MCAO 缝合线诱导中风模型将通过减少不完全闭塞和颅内出血的发生来提高您的模型质量。使用 Doccol MCAO 缝合线,您将能够实现高度一致的梗塞以及低死亡率。除了卓越的产品质量外,Doccol 还提供种类繁多的 MCAO 缝合线,旨在满足中风研究人员的多样化需求。多年来,我们的 MCAO 缝合线一直被中风研究人员优选用于诱导中风模型。据报道,使用 Doccol MCAO 缝合线诱导 MCAO 模型能够将梗塞体积的标准偏差降低到其相应平均值的 5%;这种建模方法正在成为确保 MCAO 模型最高质量的方法论新标准。有关更多信息,请阅读 Doccol 在笔画建模方面有所作为。

2010 年,Doccol 注意到大多数实验室进行的微血管导管插入术对于血液检测和药物输送都不方便。那些“微导管”有一个需要连接针头的过渡管,当压力高时它可能会破裂,并且可能会在连接到同步环之前意外刺入操作员的手指。这些导管还具有很大的内部体积,必须处理以进行药物输送。 Doccol 提供了专门设计的微导管,用于提高啮齿动物血液采样、药物输送、小流量液体转移和生理监测的性能、质量和生产力,其中需要侵入性血管通路。我们的微导管永久连接到工业标准 Luer 锁或旋塞阀,因此消除了过渡管和针头连接,并显着减少了内部体积。 Doccol 为所有常见位置的血管插管提供了足够的微导管选择,例如尾部、股骨、颈动脉和肱静脉和动脉,以及颈静脉。

在我们多年专注于中风研究的服务中,Doccol 也开始提供我们精心挑选的必要显微手术工具和设备,并于 2019 年开发了其独特的基于 Arduino 的 PID 温度控制器。这些必不可少的工具和设备可确保您的实验性中风研究具有高质量和高生产力。

Doccol is a biotech company that started from solving real problems in biological research. In 2004, Doccol identified one of the key problems in experimental stroke research is the inconsistent quality of stroke models, and thence provided a solution for this by offerring standardized occluders, the silicone rubber-coated monofilaments,  for middle cerebral artery occlusion (MCAO). Those MCAO occluders  were liked very much by stroke reaearchers and given the name "MCAO sutures".  Our delicate silicone rubber-coated monofilaments are specially designed and manufactured for inducing the intraluminal filament model of MCAO, which has been widely used for in vivo experimental stroke studies. Using Doccol MCAO sutures for inducing stroke models will improve your model quality by reducing the occurrence of both the incomplete occlusion and the intracranial bleeding. With Doccol MCAO sutures, you will be able to achieve a highly consistent infarct as well as a low mortality rate. In addition to the super product quality, Doccol provides MCAO sutures with a great variety that was designed to meet the diverse demand from stroke investigators. For many years our MCAO sutures have been preferably selected by stroke investigators for inducing stroke models. Using Doccol MCAO sutures for inducing MCAO models has been reported to be able to reduce the standard deviation to 5% of its corresponding mean value as for infarction volume; and this modeling method is becoming a methodological new standard for ensuring the highest quality of MCAO models. For more information please read Doccol Made a Difference in Stroke Modeling.

In 2010, Doccol noticed that microvascular catheterization procedures performed in most laboratories are inconvinient for both blood testing and drug delivery. Those "microcatheters" have a transition tubing requiring a needle connection, which may break when pressure is high, and may accidentally puncture into the operator's finger, before it can be connected to a synringe. These catheters also have a large inner volume that has to be dealt with for drug delivery. Doccol offerred specially designed microcatheters for improving performance, quality and productivity in rodent blood sampling, drug delivery, small flow rate liquid transferring, and physiological monitoring, in which invasive vascular access is necessary. Our microcatheters are permanently connected to an industrial standard Luer lock or stopcock, therefore, eliminated the transitional tubing and needle connection and also dramatically reduced inner volume. Doccol provides sufficient choices of micro catheters for vascular cannulation in all common locations, such as the tail, femoral, carotid, and brachial veins and arteries, and also the jugular veins.

During years of our dedicated services in stroke research, Doccol also started to provide our carefully-selected essential microsurgical tools and devices, and in 2019 Doccol developed its unique Arduino-based PID temperature controllers. These essential tools and devices ensure your experimental stroke research with high quality and high productivity.


1Doccol602156PK5Re小鼠 6-0 fine MCAO suture L56 Re PK55根/管
2Doccol602356PK5Re小鼠 6-0 medium MCAO suture L56 reusable PK5 5根/管
3Doccol701934PK5Re小鼠 7-0 fine MCAO suture Re L34 PK5 5根/管
4Doccol403556PK5Re大鼠 4-0 fine MCAO suture L56 reusable PK5 5根/管
大鼠 4-0 medium MCAO suture L56 reusable PK5 5根/管




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